Histological Findings in the Paterson-kelly Syndrome.

Forty-one specimens taken from lesions in the post-cricoid region of patients with the Paterson-Kelly syndrome have been examined. Most webs consist of normal oesophageal mucosa which may be associated with underlying muscle and nerve lesions. Strictures also show a chronic non-specific inflammation often with epithelial changes and sometimes squamous carcinoma. Other lesions observed clinically have also shown malignant change.